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Interleukin-2 Soluble Receptor alpha
Test CodeLAB00115
Alias/See Also
LAB00115
LabCorp TC: 142455
IL-2R ,IL2SR, IL-2
LabCorp TC: 142455
IL-2R ,IL2SR, IL-2
CPT Codes
83520
Preferred Specimen
0.5 mL Serum
Marble/Gold/Red Top
Marble/Gold/Red Top
Minimum Volume
0.3 mL Serum
Transport Temperature
Frozen
Specimen Stability
Frozen: 14 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Thawed specimen
Methodology
Immunochemiluminometric assay (ICMA)
Report Available
3-6 days
Limitations
This test was developed and its performance characteristics determined by LabCorp. it has not been cleared or approved by the Food and Drug Administration.
sIL-2Rα level is only one out of eight criteria of which five have to be met to make a diagnosis. The combination of these clinical and laboratory criteria shoudl warrant sufficent specificity. In order to reach a high specificity close to 100%, levels >10,000 U/mL are required.
The clinical presentation of HLH can have considerable overlap wiht other inflammatory conditions. A normal or only modestly elevated sIL-2Rα
sIL-2Rα level is only one out of eight criteria of which five have to be met to make a diagnosis. The combination of these clinical and laboratory criteria shoudl warrant sufficent specificity. In order to reach a high specificity close to 100%, levels >10,000 U/mL are required.
The clinical presentation of HLH can have considerable overlap wiht other inflammatory conditions. A normal or only modestly elevated sIL-2Rα
Reference Range
Interleukin-2-soluble-receptor:
223-710 units/mL
223-710 units/mL
Clinical Significance
This test is used for the measurement of Interleukin-2 Soluble Receptor α (sIL-2Rα) levels in serum.
Performing Laboratory
LabCorp