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TISSUE TYPING-OSU
MessageKit is supplied by OSU with all shipping labels.
Note: If test is ordered by Nationwide Childrens, specimen is sent to NCH Childlab.Send copy of order with specimen.
Note: If test is ordered by Nationwide Childrens, specimen is sent to NCH Childlab.Send copy of order with specimen.
Test Code
TISSTYPE
Alias/See Also
Alloscreen
Preferred Specimen
RED TOP TUBE (DO NOT SPIN OR OPEN TUBE)
Other Acceptable Specimens
OSU WILL ACCEPT A SPUN TUBE IF NOT THE FIRST PRETESTING SAMPLE
Instructions
DO NOT SPIN
Clinical Significance
Typing performed by Sequence Based Testing (SBT). Some testing may be performed by DNA, SSP-PCR. Testing performed by the OSUMC Clinical Histocompatibility
DNA is extracted from donor and recipient cells, then manipulated in such a way as to amplify specific regions or fragments on a chromosome and within the HLA genes. The amplified fragments are subjected to further analysis that allows for comparison of the polymorphisms in the HLA between the donor and the recipient. This careful analysis of genetic material results in fewer rejection reactions and a greater chance for a successful transplant.
DNA is extracted from donor and recipient cells, then manipulated in such a way as to amplify specific regions or fragments on a chromosome and within the HLA genes. The amplified fragments are subjected to further analysis that allows for comparison of the polymorphisms in the HLA between the donor and the recipient. This careful analysis of genetic material results in fewer rejection reactions and a greater chance for a successful transplant.
Performing Laboratory
OSH- TRANSPLANT DEPT.