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Factor IX Activity and Inhibitor
Message*Take to processing ASAP
Requires WildCode
Call Carrie x4171 or Amber x4173
Requires WildCode
Call Carrie x4171 or Amber x4173
Test Code
LAB3004
Alias/See Also
LAB3004
Coagulation Factor IX Evaluation
Factor 9 Evaluation
Coagulation Factor IX Evaluation
Factor 9 Evaluation
CPT Codes
85250, 85335
Preferred Specimen
2 mL (x2) frozen plasma collected in a 3.2% sodium citrate (light blue-top) tube
Minimum Volume
1mL (x 2)
Instructions
Submit a total of 4mL (1-2mL in each of 2 tubes).
Centrifuge light blue-top tube 15 minutes at approx. 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcl). Freeze immediately and ship on dry ice.
Centrifuge light blue-top tube 15 minutes at approx. 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcl). Freeze immediately and ship on dry ice.
Transport Container
Transport Temperature
Frozen
Specimen Stability
Frozen: 14 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature • Received refrigerated
Clinical Significance
Factor IX Activity is useful to evaluate a prolonged aPTT. The second most common form of hemophilia is caused by deficiency of factor IX. Hemophilia B is an x-linked disorder affecting between 1 in 25,000 to 30,000 males.
Factor IX Human Inhibitor provides a quantitative determination of inhibitors. This aids in developing treatment strategies for patients with hemophilia.
Factor IX Human Inhibitor provides a quantitative determination of inhibitors. This aids in developing treatment strategies for patients with hemophilia.
Performing Laboratory
Quest Diagnostics