RET Proto-Oncogene, Full Gene Analysis

Message

*Draw Monday-Thursday before 2:30pm. Do not collect on weekends or holidays.

Test Code

LAB00460

Alias/See Also

LAB00460
Mayo TC: RETZZ
Mayo Test Name: Multiple Endocrine Neoplasia Type 2 Syndrome, RET, Full Gene Analysis, Varies

CPT Codes
81406

Physician Attestation of Informed Consent

Providers: Informed consent and education are required prior to drawing specimen! Please see Instructions below.

Preferred Specimen

3.0 mL Lavender (EDTA) - Whole Blood

Minimum Volume

1.0 mL Lavender (EDTA) - Whole Blood

Other Acceptable Specimens

Yellow Top (ACD) - Whole Blood

Instructions

REQUIRES ORDER FORM T729 AND ADDITIONAL INFORMATION FORM T576 SENT TO MAYO
https://www.mayocliniclabs.com/it-mmfiles/MC1235-97_Molecular_Genetics-Congenital_Inherited_Diseases_Patient_Information.pdf
https://www.mayocliniclabs.com/it-mmfiles/Informed_Consent_for_Genetic_Testing.pdf

Transport Temperature

Room Temperature

Specimen Stability

Room Temperature: 4 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Methodology
Sequence Capture and Targeted Next-Generation Sequencing (NGS) followed by Polymerase Chain Reaction (PCR) and Sanger Sequencing

Report Available

21-28 days

Clinical Significance

Evaluating patients with a personal or family history suggestive of a multiple endocrine neoplasia type 2 (MEN2) or Hirschsprung disease (HSCR).
Establishing a diagnosis of MEN2 or HSCR allowing for targeted cancer surveillance based on associated risks.
Identifying varients within genes known to be associated with MEN2 or HSCR allowing for predictive testing of at-risk family members.

Performing Laboratory
Mayo Clinic

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.