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Porphyrins, Stool (24, 48, 72, or 96 hour collection)
MessageCollect a stool specimen for either 24, 48, 72, or 96 hours. (24 hour collection is adequate if the collection volume is approximately 100g)
Need a list of medications the patient is currently taking.
Record total weight of specimen and document the duration of collection.
Need a list of medications the patient is currently taking.
Record total weight of specimen and document the duration of collection.
Test Code
LAB00458
Alias/See Also
LAB00458
Mayo TC: FQPPS
Mayo Test Name: Porphyrins, Feces
Mayo TC: FQPPS
Mayo Test Name: Porphyrins, Feces
CPT Codes
84126
Preferred Specimen
24, 48, 72, or 96 hour stool collection
Minimum Volume
24 hour stool collection with a minimum volume of 100g.
Transport Temperature
Refrigerated
Specimen Stability
Refrigerated: 14 days
Methodology
High-Performance Liquid Chromatography (HPLC)
Report Available
3-7 days
Limitations
Heme from red meat can contibute to fecal protoporphyrin concentrations and cause a misleading indication of erythropoietic protoporphyria, X-linked dominant protoporphyria, or variegate porphyria.
Asprin ingestion may cause minimal gastrointestinal bleeding, leading to false elevations of protoporphyrin.
Specimen submitted should contain at least 100g of feces. Specimens smaller than 100g may not provide interpretable results. Specimens weighing less than 10 grams will be rejected.
Asprin ingestion may cause minimal gastrointestinal bleeding, leading to false elevations of protoporphyrin.
Specimen submitted should contain at least 100g of feces. Specimens smaller than 100g may not provide interpretable results. Specimens weighing less than 10 grams will be rejected.
Clinical Significance
Evaluation of patients who present with signs or symptoms suggestive of porphyria cutanea tarda, hereditary coproporphyria, variegate porphyria, congenital erythropoietic porphyria, erythropoietic protoporphyria, or X-linked dominant protoporphyria.
Performing Laboratory
Mayo Clinic Laboratories