Lymphocyte Proliferation to Antigen and Lymphocyte Proliferation to Mitogens

Message
DRAW M-TH BEFORE NOON ONLY! Must send out to Mayo same day as drawn.
SEND TO MAYO. REQUEST TEST CODES LPMGF (LAB00939) AND LPAGF (LAB00940).

*On adults this test combined needs 6-8 Dark Green top tubes*
Children 6-18 yrs draw 3 Dark Green top tubes
Children 2-5 yrs draw 2 Dark Green top tubes
Children less than 2 yrs draw 1 Dark Green top tube


Test Code
LAB00940/LAB00939


Alias/See Also
Order both: LAB00939 & LAB00940
Lymphocyte Proliferation Panel
Mayo TC: LPAGF & LPMGF


CPT Codes
86353X2

Preferred Specimen
20 mL Dark Green Top (Sodium Heparin) - Whole Blood - Per Test = 40 mL for both 
Collect 6-8 Dark Green Top tubes when performing both tests on adults
Collect 3-4 Dark Green Top tubes when performing both tests on patients 25 months to 18 yearr
Collect 1-2 Dark Green Top tubes when performing both tests on patients 3 - 24 months
Collect 1 Dark Green Top tube when performing both tests on patients <3 months


Transport Temperature
Room Temperature


Specimen Stability
Room Temperature: 48 hours - Must ship same day as collected.


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis, Gross lipemia


Methodology
Flow Cytometry

Report Available
11-14 days


Clinical Significance
Assessing T-cell function in patients on immunosuppressive therapy, inculding solid-organ transplant patients.
Evaluating patients suspected of having impairment in cellular immunity.
Evaluation of T-cell function in patients with primary immunodeficiencies, either cellular (DiGeorge syndrome, T-negative severe combined immunodeficiency [SCID], etc) or combined T- and B-cell immunodeficiencies (T- and B- negative SCID, Wiskott Aldrich syndrome, ataxia telangiectasia, common variable immunodeficiency, among others) where T-cell function may be impaired.
Evaluation of T-cell function in patients with secondary immunodeficiency, either disease related or iatrogenic.
Evaluation of recovery of T-cell function and competence following bone marrow transplantation or hematopoietic stem cell transplantation.
This test is NOT intended for assessment of maternal engraftment. 


Performing Laboratory
Mayo Clinic Laboratories



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.