Hydroxyproline, Total

Message
Require WildCode
Call Carrie x4171 or Amber x4173


Test Code
LAB1036


Alias/See Also
LAB1036


CPT Codes
83500

Preferred Specimen
2.0 mL Dark Green Tube (Sodium Heparin) - Plasma


Minimum Volume
0.5 mL Dark Green Tube (Sodium Heparin) - Plasma


Instructions
FASTING OR 4 HOURS AFTER A MEALWILD CODE TO QUEST


Transport Temperature
Frozen


Specimen Stability
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis, Received at room temperature


Methodology
Chromatography/Mass Spectrometry

Clinical Significance
Hydroxyproline is necessary for the construction of collagen. Defects in collagen synthesis lead to easy bruising, internal bleeding, breakdown of connective tissue of the ligaments and tendons, and increased risk to blood vessel damage. Increased loss of hydroxyproline in the urine is generally associated with breakdown of connective tissue, due to disease processes and may also be a manifestation of vitamin C deficiency.


Performing Laboratory
Quest Diagnostics



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.