Anti-Th/To Ab

Test Code
91290


Alias/See Also
LAB00320


CPT Codes
83516

Preferred Specimen
1 mL serum


Minimum Volume
0.3 mL


Instructions
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.


Transport Container
Transport tube


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 60 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Lipemia • Bacterial contamination • Icteric • Non-serum specimen types


Methodology
Radio Immunoprecipitation Assay Gel Radiography

FDA Status
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.

Setup Schedule
Varies


Report Available
16 days


Reference Range
Negative


Clinical Significance
The Th/To antibodies are present in 10-19% of patients with limited SSc, in 11% of patients with diffuse cutaneous SSc, and in 3% of patients with primary Raynaud's disease. Anti-Th/To antibody has been shown to be highly specific for patients with SSc.


Performing Laboratory
Esoterix Endocrinology
4301 Lost Hills Road
Calabasas Hills, CA 91301-5358




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.