Myasthenia Gravis Profile

Test Code
LAB01057


Alias/See Also
LAB01057
LabCorp TC: 165620


CPT Codes
86255, 86041, 86042, 86043

Includes
AChR Binding
AChR Blocking
AChR Modulating 
Striational Antibodies
Reflexes to MuSK antibodies if AChR-Binding and blocking are normal.


Preferred Specimen
4mL Serum divided into 2 tubes
(Marble/Gold)


Patient Preparation
No isotopes administered 24 hours prior to venipuncture.

Minimum Volume
2mL Serum 


Instructions
Allow a minimum clotting time of 30 to 60 minutes with serum separation within 2 hours of collection. Send serum samples in plastic transport tubes. 


Transport Temperature
Refrigerated


Specimen Stability
Refrigerated: 14 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Excessive hemolysis, chylous serum, recently administered radioisotopes, plasma


Report Available
6-8 days


Limitations
In rare cases AChR antibodies can be found in patients with other autoimmune disorders or with thymoma without MG.
The causative autoantibody cannot be identified in up to 10 percent of patients with MG.
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.


Clinical Significance
Tests for the laboratory diagnosis of myasthenia gravis (MG).


Performing Laboratory
LabCorp



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.