19911A>G Mutation Analysis [16533X]

Test Code
16533

CPT Codes
<p>81400<br /> <br /> This code is for non-New York State clients only. For New York State patient testing, use<br /> code 16534X [16534], 19911A&gt;G Mutation Analysis**NY Only**.&nbsp;</p>

Physician Attestation of Informed Consent
This germline genetic test requires physician attestation that patient consent has been received if ordering medical facility is located in AK, AZ, DE, FL, GA, MA, MN, NV, NH, NJ, NM, NY, OR, SD or VT or test is performed in MA.

Preferred Specimen
5 mL whole blood collected in an EDTA (lavender-top) tube

Minimum Volume
3 mL

Other Acceptable Specimens
Whole blood collected in: ACD solution A or B (yellow-top) tube • Lithium or sodium heparin (green-top) tube

Transport Container
EDTA (lavender-top) tube

Transport Temperature
Room temperature

Specimen Stability
Room temperature: 8 days
Refrigerated: 8 days
Frozen: Unacceptable

Methodology
Capillary Electrophoresis • Fluorescence Detection • Polymerase Chain Reaction Amplification • Single Nucleotide Extension

This test was developed and its performance characteristics have been determined by Quest Diagnostics. Performance characteristics refer to the analytical performance of the test.



Reference Range
See Laboratory Report

Clinical Significance
This test can be used to detect the 19911A→G polymorphism in the prothrombin (Factor II) gene which may modulate the risk of deep vein thrombosis in patients with the G20210A mutation.



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.