Urine Total Protein Quantitative

Test Code

URTP

CPT Codes
84156

Includes

Random Specimen includes Urine Total Protein. Timed Specimen includes Urine Volume, Hours Collected, Urine Total Protein, and Total Protein/Total Volume Ratio.

Preferred Specimen

Random or Timed Urine Specimen

Minimum Volume

1 mL

Instructions

This test is for quantitative Total Protein measurement on Urine. For urine protein measurement as performed by urinalysis method, order UPRO. For Total Protein Measurement on Plasma or Serum, order TP. For Total Protein measurement on Body Fluids other than CSF, order MISTP. For Total Protein measurement on CSF, order CSFTP (or CSFP for CSF Profile).

Transport Container

24-hour urine container or sterile urine cup

Transport Temperature

Refrigeration

Specimen Stability

3 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Quantity Not Sufficient

Methodology
Colorimetric

Setup Schedule

Monday - Sunday, 8:00am - 3:00 pm upon receipt

Report Available

Upon completion of analysis

Limitations

Hemolysis may cause a falsely elevated result. Hemoglobin is a protein and its presence in urine results in an increase in measured protein. Urine samples should not be collected after intense physical exertion or acute fluid load or deprivation. Collect specimens prior to the administration of contrast media. Some of these media may cause a significant bias.

Reference Range

Urine Volume: 800 - 1800 mL/24 hours
Urine Total Protein/Total Volume Ratio: 0.4 - 1.3 g/24 hours

Clinical Significance

Urine Protein measurement is useful in evaluation of renal disease and screening for monoclonal gammopathy.

Protein in urine is normally composed of a combination of plasma-derived proteins that have been filtered by glomeruli and have not been reabsorbed by the proximal tubules and proteins secreted by renal tubules or other accessory glands.

Increased amounts of protein in the urine may be due to:

-Glomerular proteinuria: caused by defects in permselectivity of the glomerular filtration barrier to plasma proteins (eg, glomerulonephritis or nephrotic syndrome)

-Tubular proteinuria: caused by incomplete tubular reabsorption of proteins (eg, interstitial nephritis)

-Overflow proteinuria: caused by increased plasma concentration of proteins(s) (eg, multiple myeloma, myoglobinuria)

-Urinary tract inflammation or tumor

Low-grade proteinuria may be seen in inflammatory or neoplastic processes involving the urinary tract.

This test is for Total Protein measurement on Urine. For Total Protein Measurement on Plasma or Serum, order TP. For Total Protein measurement on Body Fluids other than CSF, order MISTP. For Total Protein measurement on CSF, order CSFTP (or CSFP for CSF Profile).

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.