Urine Glucose Quantitation

Test Code

URGLU

CPT Codes
82945

Includes

Random Specimen includes Urine Glucose. Timed Specimen includes Urine Volume, Hours Collected, Urine Calcium, and Calcium/Total Volume Ratio.

Preferred Specimen

Random or Timed urine specimen.

Minimum Volume

1 mL

Instructions

Collect random or timed specimen per orders. For timed specimen, record start and stop time of collection or number of hours. To transfer specimen from large container to smaller container for transport, measure volume first and record on smaller container, along with start/stop time or hours of collection. Timed specimens are typically collected for 24 hours, but can be collected in other increments, for example, 4 hours or 12 hours.

This test is for Glucose measurement on Urine.

Other Glucose Orders:

Fasting or Random Glucose on Plasma/Serum:     GLU
Post-Prandial Glucose on Plasma/Serum:     GLUPC
Gestational Glucose Toleranse Test on Plasma/Serum:
               GTTGES
Glucose Tolerance Test:     GTT
Glucose on Body Fluids other than CSF:   MISGLU
Glucose on CSF:     CSFGLU (or CSFP for CSF Profile)

Transport Container

24-hour urine container or sterile urine cup

Transport Temperature

Refrigeration

Specimen Stability

3 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Quantity Not Sufficient

Methodology
Colorimetric

Setup Schedule

Monday - Sunday, 8:00 am - 3:00 pm upon receipt

Report Available

Upon completion of analysis

Reference Range

Urine Volume: 800 - 1800 mL/24 Hours
Glucose/Total Volume: 0 - 500 mg/24 Hours

Clinical Significance

Urine Glucose measuremement is an indicator of abnormal proximal tubule function and has limited usefulness in the screening or management of diabetes mellitus

Under normal circumstances, glucose is readily filtered by glomeruli and the filtered glucose is reabsorbed by the proximal tubule; essentially no glucose is normally excreted in the urine. However, the capacity for the proximal tubule to reabsorb glucose is limited; if the filtered load exceeds the proximal tubule's reabsorptive capacity, a portion of the filtered glucose will be excreted in the urine. Thus, elevated serum glucose concentrations (as seen with diabetes mellitus) may result in an increase in filtered load of glucose and may overwhelm the tubules' reabsorptive capacity resulting in glucosuria. Glucosuria occurs when the renal threshold for glucose is exceeded (typically >180 mg/dL). This is most commonly, although not exclusively, seen in diabetes.

Additionally, conditions which adversely affect proximal tubule function may also result in decreased reabsorption of glucose, and increased urinary glucose concentration, even in the presence of normal plasma glucose concentrations. Some of these conditions include Fanconi syndrome, Wilson disease, hereditary glucosuria, and interstitial nephritis. These conditions are relatively rare, and most causes for elevated urine glucose concentrations are due to elevated serum glucose levels.

Elevated urine glucose concentration reflects either the presence of hyperglycemia or a defect in proximal tubule function.

As a screening test for diabetes mellitus, urine glucose testing has a low sensitivity (though reasonably good specificity).

This test is for Glucose measurement on Urine.

Other Glucose Orders:

Fasting or Random Glucose on Plasma/Serum:     GLU
Post-Prandial Glucose on Plasma/Serum:     GLUPC
Gestational Glucose Toleranse Test on Plasma/Serum:
               GTTGES
Glucose Tolerance Test:     GTT
Glucose on Body Fluids other than CSF:     MISGLU
Glucose on CSF:     CSFGLU (or CSFP for CSF Profile)

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.