Urine Creatinine

Test Code
URCRN


CPT Codes
82570

Includes
Random Specimen includes Urine Creatinine. Timed Specimen includes Urine Volume, Hours Collected, Urine Creatinine, and Creatinine/Total Volume Ratio.


Preferred Specimen

Random or timed urine specimen



Minimum Volume
1 mL


Instructions

Collect random or timed specimen per orders.  For timed specimen, record start and stop time of collection or number of hours.  To transfer specimen from large container to smaller container for transport, measure volume first and record on smaller container, along with time.  Timed specimens are typically collected for 24 hours, but can be collected in other increments, for example, 4 hours or 12 hours.

This test is for Urine Creatinine and requires only urine collection.  For Creatinine Clearance, order 24CC.  Blood draw is also required for 24CC testing.  For Creatinine measurement on Plasma or Serum only, order CREAT.  For Creatinine measurement on Plasma or Serum and an Estimated Glomerular Filtration Rate, order CRNGFR.  For Creatinine measurement on Body Fluids, order MISCRN.



Transport Container

24-hour urine container or sterile urine cup



Transport Temperature
Refrigeration


Specimen Stability
3 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Quantity Not Sufficient


Methodology
Colorimetric

Setup Schedule

Monday - Sunday, 8:00 am - 3:00 pm upon receipt



Report Available
Upon completion of analysis


Reference Range

Urine Volume:  800 - 1800 mL/24 hours
Urine Creatinine/Total Volume Ratio:  0.8 - 2.8 g/24 hours



Clinical Significance

Serum creatinine and urinary creatinine excretion is a function of lean body mass in normal persons and shows little or no response to dietary changes.  The serum creatinine concentration is higher in men than in women.  Since urinary creatinine is excreted mainly by glomerular filtration, with only small amounts due to tubular secretion, serum creatinine and a 24-hour urine creatinine excretion can be used to estimate the glomerular filtration rate.  Serum creatinine is increased in acute or chronic renal failure, urinary tract obstruction, reduced renal blood flow, shock, dehydration, and rhabdomyolysis.  Causes of low serum creatinine concentration include debilitation and decreased muscle mass.  Exercise may cause an increased creatinine clearance. The creatinine clearance rate is unreliable if the urine flow is low.

This test is for Urine Creatinine and requires only urine collection.  For Creatinine Clearance, order 24CC.  Blood draw is also required for 24CC testing.  For Creatinine measurement on Plasma or Serum only, order CREAT.  For Creatinine measurement on Plasma or Serum and an Estimated Glomerular Filtration Rate, order CRNGFR.  For Creatinine measurement on Body Fluids, order MISCRN.





The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.