Total Protein, Serum or Plasma

Test Code
TP


CPT Codes
84155

Preferred Specimen

Serum (gold top) tube



Minimum Volume
0.5 mL


Other Acceptable Specimens
Lithium Heparin Plasma (green top) tube


Instructions

This test is for Total Protein measurement on Serum or Plasma. For a Total Protein measurement on Body Fluids (except CSF), order MISTP.  For Total Protein measurement on CSF, order CSFTP (or CSFP for CSF Profile).  For Total Protein measurement on urine, order URTP or UPRO (urinalysis method).



Transport Container

Serum (gold top) tube or Lithium Heparin Plasma (green top) tube



Transport Temperature
Room Temperature or Refrigeration


Specimen Stability
Room Temperature - 4 hours; Refrigerated - 3 days


Methodology
Colorimetric

Setup Schedule

Daily upon receipt



Report Available
Upon completion of analysis


Reference Range

Birth - 2 Years:      4.6 - 7.6 g/dL
2 Years - Adult:     6.3 - 8.2 g/dL
 

Please note, Serum or Plasma Total Protein is measured in g/dL, whereas Body Fluid Total Protein is measured in mg/dL.



Clinical Significance

Serum proteins transport drugs and metabolites and maintain plasma osmotic pressure. Most serum proteins are synthesized in the liver, with the exception of gamma globulins. One of the most important serum proteins produced in the liver is albumin. Total serum protein concentration can be used for evaluation of nutritional status. Causes of high total serum protein concentration include dehydration, Waldenström’s macroglobulinemia, multiple myeloma, hyperglobulinemia, granulomatous diseases, and some tropical diseases. Total protein concentration is occasionally increased in collagen diseases, lupus erythematosus, and other instances of chronic infection or inflammation. Causes of low total serum protein concentration include pregnancy, excessive intravenous fluid administration, cirrhosis or other liver diseases, chronic alcoholism, heart failure, nephrotic syndrome, glomerulonephritis, neoplasia, protein-losing enteropathies, malabsorption, and severe malnutrition.

This test is for Total Protein measurement on Serum or Plasma. For a Total Protein measurement on Body Fluids (except CSF), order MISTP.  For Total Protein measurement on CSF, order CSFTP (or CSFP for CSF Profile).  For Total Protein measurement on urine, order URTP.





The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.