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Sweat Test
Test CodeSWEAT
CPT Codes
89230
Preferred Specimen
Sweat - 50uL
Minimum Volume
20 uL
Other Acceptable Specimens
none
Instructions
SWEAT TEST - NOTIFY IMMUNOLOGY; Run in-house M-F, 8:00-3:00. Outpatients done on Tuesdays only. PATIENT MUST NOT BE FASTING!
Transport Container
LABEL/1
Specimen Stability
72 hours refrigerated
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
QNS; patient being unable to sweat
Methodology
COND
Setup Schedule
Tues for outpatient; daily for inpatient
Report Available
24
Limitations
Patient must not be fasting.
Reference Range
Normal - <80 mmol/L; Cystic Fibrosis - Greater than 90 mmol/L; Cystic Fibrosis founation recommends values greater than 50 mmol/L be confirmed by sweat electrolyte testing.
Clinical Significance
Fibrocystic disease (mucoviscidosis) is a familial,mendelian-recessive disease characterized by abnormal secretion of the various exocrine glands of the body. Involvement of the intestinal glands may result in the presence of meconium ileus at birth. Chronic lung disease and malabsorption resulting from pancreatic involvement are the major clinical problems of those who survive beyond infancy. It is well-established that children afflicted with cystic fibrosis show clearly elevated electrolyte concentration in their sweat.