Rubella Antibodies, IgG

Test Code

RUB

CPT Codes
86762

Preferred Specimen

Red top serum tube

Minimum Volume

0.5 mL

Other Acceptable Specimens

Lithium Heparin Plasma (green top) tube

Instructions

This test is for Rubella IgG antibodies. Order Rubeola (Measles) separately.

Transport Temperature

Room Temperature or Refrigeration

Specimen Stability

Room Temperature - 1 day; Refrigerated - 7 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Turbidity, Quantity Not Sufficient, IV contamination

Methodology
Chemiluminescence

Setup Schedule

Daily upon receipt

Report Available

Upon completion of analysis

Reference Range

Interpretation:

< 5.0 IU/mL = Susceptible
5.0 - 9.9 IU/mL = Equivocal
> OR = 10 IU/mL = Immune

Equivocal levels may not provide immunity. Retesting with new specimen recommended.

Clinical Significance

Acute rubella viral infection is usually a mild, self limited, benign disease of short duration with symptoms that include low-grade fever and a rash. However infection of the fetus during the first trimester of pregnancy may result in severe congenital abnormalities (congenital rubella syndrome). IgM antibodies to the virus appear and decrease rapidly within 4 to 5 weeks after the onset of symptoms, but IgG antibodies usually persist for life. Rubella tests may be used to define immune status and to determine the need for vaccination, to evaluate vaccine efficacy and as an aid to the diagnosis of recent infection. The patient groups normally tested are women of childbearing age, pregnant women or healthcare workers who may have close contact with a confirmed rubella case or have the clinical indicators of rubella viral infection.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.