RPR

Test Code
RPR


Alias/See Also
Rapid Plasma Reagin


CPT Codes
86592

Preferred Specimen

Red




Minimum Volume
0.5 ml


Other Acceptable Specimens
EDTA plasma


Instructions

Serum samples should be tested with 5 days. Samples that require longer storage periods must be removed from the red cells and stored at 2-8C for 5 days. Store serum at -20C or below if longer that 5 days. **Plasma samples stored longer that 48 hours should not be used.***



Transport Container

RED/1



Transport Temperature
Room temp


Specimen Stability
7 days at 2-8 C


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolyzed, lipemia, bacterial contamination


Methodology
MAN

Setup Schedule

Daily upon receipt



Report Available
Upon completion of analysis


Limitations
Specimens must be free from baterial contamination, hemolysis or lipemia.


Reference Range

Non-Reactive



Clinical Significance

The RPR test is a qualitative and semiquautitative non-treponemal flocculation test for the detection of reagin antibodies in human serum and plasma as a screening test in syphilis serology. Treponema pallidium, the etiological agent of syphilis, induces the production of at least two types of antibodies in human infection: (1)anti-treponemal antibodies that can be detected by FTA-ABS antigen, and (2)anti-treponemal antibodies(reagin) that can be detected by RPR antigen.





The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.