| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Progesterone
Test CodeCPT Codes
84144
Preferred Specimen
Green
Minimum Volume
Other Acceptable Specimens
Transport Container
Serum (gold top) tube or Lithium Heparin Plasma (green top) tube
Transport Temperature
Specimen Stability
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Methodology
Chemiluminescence
Setup Schedule
Daily upon receipt
Report Available
Reference Range
Interpretation:
Female:
Follicular Phase: 0.1 - 1.7 ng/mL
Peri-Ovulatory Phase: 0.4 - 5.9 ng/mL
Mid-Luteal Phase: 6.0 - 24.0 ng/mL
Luteal Phase: 1.0 - 22.4 ng/mL
Clinical Significance
The main sites of progesterone production are the adrenal cortex, ovaries, and corpus luteum following ovulation and the placenta by the twelfth week of pregnancy. Circulating progesterone is bound to several serum proteins including albumin and corticosteroid binding globulin. The physiologically active free hormone represents approximately 3% of the total progesterone concentration. Measurement of serum progesterone is useful in the investigation of ovarian function where disorders of ovulation are responsible for infertility in 15–20% of patients, and for predicting ovulation in induced cycles, where concentrations are generally higher than normal. Properly timed measurements of progesterone can be used in the diagnosis of patients with recurrent and threatened abortion in the first ten weeks of gestation. Corpus luteum dysfunction is indicated by lower than normal progesterone concentrations.