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Chemistry Profile (Neonatal)
Test CodeN-CHEM
Alias/See Also
Neonatal Chemistry Profile
CPT Codes
80053
Includes
Sodium, Potassium, Chloride, Carbon Dioxide, Anion Gap, Glucose, Blood Urea Nitrogen, Creatinine, BUN/Creatinine Ratio, Calcium, Alkaline Phosphatase, SGOT (AST), SGPT (ALT), Total Neonatal Bilirubin, Total Protein, Albumin
Preferred Specimen
Serum (gold top) tube
Minimum Volume
0.5 mL (500 uL)
Other Acceptable Specimens
Lithium Heparin Plasma (green top) tube
Instructions
Protect specimen from prolonged exposure to light using a brown paper sack, aluminum foil, or a dark-colored tube.
Transport Container
Serum (gold top) tube or Lithium Heparin Plasma (green top) tube
Transport Temperature
Room Temperature or Refrigeration
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis, Quantity not Sufficient, EDTA contamination, IV contamination
Methodology
Colorimetric, Potentiometric
Setup Schedule
Daily upon receipt
Report Available
Upon completion of analysis
Limitations
Heparinized catheters may contain benzalkonium chloride and should not be used for collection due to interference with testing. Do not use specimens obtained through catheters used to infuse hyperalimentation fluid. Blood from patients receiving Hypaque radiographic contrast agent cannot be used due to interference with calcium testing. Do not use blood on patients receiving EDTA therapy. Suramin, an antiparasitic drug, has been reported to cause a bias of -10% in calcium results at a suramin concentration of 300 μg/mL. Calcium results from recumbent patients may be 3% lower. Blood collected with stasis may have calcium concentrations 15% higher. Ammonium ions may cause an increase in measured BUN/UREA value equivalent to the specimen’s nitrogen content. Albumin concentrations vary with posture. Results from an upright posture may be approximately 0.3 g/dL higher than those from a recumbent posture. A delay in centrifugation of several hours can result in a falsely increased potassium result and a falsely decreased glucose result.