Lidocaine, Serum

Test Code

LIDO

Alias/See Also

Xylocaine

CPT Codes
80176

Preferred Specimen

Serum (gold or red top tube)

Minimum Volume

0.5 mL

Transport Container

Serum (gold or red top) tube

Transport Temperature

Room Temperature or Refrigeration

Specimen Stability

RoomTemperature - 7 days; Refrigeration - 7 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Quantity Not Sufficient, IV Contamination

Methodology
Turbidimetric

Setup Schedule

Daily upon receipt

Report Available

Upon completion of analysis

Reference Range

Therapeutic Range: 1.5 - 5.0 ug/mL

Clinical Significance

Lidocaine is an anti-arrhythmic drug commonly used to restore a regular heartbeat.

The therapeutic effectiveness and toxic side effects of lidocaine in the treatment of cardiac arrhythmias correlate better with the serum concentration than with the administered dose.

After suspected myocardial infarction, monitoring lidocaine in serum during infusion helps to establish and maintain adequate prophylactic or therapeutic drug concentrations and avoid toxicity. However, lidocaine concentration determinations are most useful when the result is obtained soon after the sample is drawn because the drug's half-life is very short (74 to 140 minutes), and the patient's potentially changing condition can unpredictably alter the drug's distribution, metabolism and elimination.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.