Lutenizing Hormone

Test Code
LH


CPT Codes
83002

Preferred Specimen

Green




Minimum Volume
0.5 mL


Other Acceptable Specimens
Lithium Heparin Plasma (green top) tube


Transport Container

Serum (gold top) tube or Lithium Heparin Plasma (green top) tube



Transport Temperature
Room Temperature or Refrigeration


Specimen Stability
Room Temperature - 1 day; Refrigerated - 5 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Turbidity, Quantity Not Sufficient, IV contamination


Methodology
Chemiluminescence

Setup Schedule

Daily upon receipt



Report Available
Upon completion of analysis


Reference Range

Female:

Follicular Phase:        2.6-12.1 mIU/mL FOLLICULAR;
Mid-Cycle:                 27.3-96.9 mIU/mL MID-CYCLE;
Luteal Phase:            0.8-15.5 mIU/mL LUTEAL;
Post-Menopausal:     13.1-86.5 mIU/mL POST-MENOPAUSE;

Males:                        1.3 - 10.5 mIU/mL



Clinical Significance

LH is a dimeric glycoprotein hormone secreted by the anterior pituitary in response to hypothalamic gonadotrophin releasing hormone. The a-subunit is common to other glycoprotein hormones, while the ß-subunit, which confers biological activity, has some homology with that of human chorionic gonadotrophin. During the menstrual cycle, follicle stimulating hormone (FSH) stimulates growth of the ovarian follicle which, when mature, ovulates in response to a surge of LH and, to a lesser extent, of FSH. Ovarian steroids are the primary negative feedback control for LH secretion. At menopause, reduced ovarian negative feedback results in elevated LH concentrations. LH concentrations also tend to be elevated in women of pre-menopausal age who experience ovarian failure, or whose ovaries failed to mature during puberty.





The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.