Lactate Dehydrogenase

Test Code

LDH

CPT Codes
83615

Preferred Specimen

Serum (gold top) tube

Minimum Volume

0.5 mL

Other Acceptable Specimens

Lithium Heparin Plasma (green top) tube

Instructions

This test is for Lactate Dehydrogenase measurement on Plasma or Serum. For Lactate Dehydrogenase measurement on Body Fluids, order MISLD.

Transport Container

Serum (gold top) tube or Lithium Heparin Plasma (green top) tube

Transport Temperature

Room Temperature

Specimen Stability

Room Temperature - 2 days; Refrigeration and Freezing are not recommended.

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis, Quantity Not Sufficient, EDTA (purple top tube) contamination, IV contamination

Methodology
Colorimetric

Setup Schedule

Daily upon receipt

Report Available

Upon completion of analysis

Reference Range

Birth - 7 Years:        470 - 920 U/L
7 - 16 Years:           420 - 750 U/L
16 Years - Adult:     313 - 618 U/L

Clinical Significance

Lactate dehydrogenase is an enzyme present in the cytosol of all human cells; it catalyzes the reversible reduction of pyruvate to lactate using NADH. Causes of high LDH include neoplastic states, hypoxic cardiorespiratory diseases, myocardial infarctions, hemolytic anemias, megaloblastic anemias, hepatic cirrhosis, renal infarction, trauma, muscle damage, muscular dystrophy, shock, and hypotension. In myocardial infarction cases, LDH begins to rise within about 12 hours after infarction and usually returns to normal after two to five days.

This test is for Lactate Dehydrogenase measurement on Plasma or Serum. For Lactate Dehydrogenase measurement on Body Fluids, order MISLD.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.