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Lactic Acid
Test CodeCPT Codes
83605
Preferred Specimen
Fluoride Oxalate Plasma (Gray Top Tube); Tube should be filled at least half full for proper blood:anticoagulant ratio.
Minimum Volume
Other Acceptable Specimens
Instructions
Fluoride Oxalate Plasma is the preferred specimen and does not require transport on ice. However, if this anticoagulant tube is not available, Lithium Heparin Plasma may be used. Transport to lab on ice within 20 minutes of collection, or centrifuge, transfer plasma to plastic pourover tube, and freeze if transport to lab will take longer than 20 minutes.
This test is for Lactic Acid measurement on Plasma. For Lacitc Acid measurement on Body Fluids, order MISLA.
Transport Container
Fluoride Oxalate Plasma Vacutainer tube, or centrifuged plasma in a plastic pourover tube. If using Lithium Heparin Plasma, specimen should be transported on ice to the lab within 20 minutes or centrifuged and plasma transferred to plastic pourover tube and frozen.
Transport Temperature
Specimen Stability
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Methodology
Colorimetric
Setup Schedule
Daily upon receipt
Report Available
Reference Range
0.7 - 2.1 mmol/L
Clinical Significance
Lactate is the end product of the anaerobic metabolism of glucose. The concentration of lactate in the blood is dependent on the rate of production in muscle cells and erythrocytes and the rate of metabolism in the liver. Lactic acidosis usually results from overproduction or underutilization of lactate. Elevated lactate levels can occur as a result of tissue hypoxia; diabetes mellitus; phenformin therapy; malignancies; glycogen storage disease; ethanol, methanol, or salicylate ingestion; and metabolic acidosis.
This test is for Lactic Acid measurement on Plasma. For Lacitc Acid measurement on Body Fluids, order MISLA.