IgA Antibodies

Test Code

IGA

CPT Codes
82784

Preferred Specimen

0.5 Red

Minimum Volume

0.5 mL

Transport Container

Serum (gold or red top) Tube

Transport Temperature

Room Temperature or Refrigeration

Specimen Stability

Room Temperature - 1 day; Refrigerated - 7 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Quantity Not Sufficient, IV contamination

Methodology
Photometric

Setup Schedule

Daily upon receipt

Report Available

Upon completion of analysis

Limitations

An abnormally elevated level of a monoclonal immunoglobulin, as in cases of multiple myeloma, amyloidosis, or other

Reference Range

70 - 400 mg/dL

Clinical Significance

IgA represents 10 to 15% of serum immunoglobulin. Despite the uncertainty of its exact role in serum, its part in resistance against infection is due to the prevention of adherence of bacteria, or to the inhibition of attachment and penetration of viruses. IgA may be elevated in recurrent infections and anaphylactic transfusion reactions. Increases are also associated with chronic liver disease, chronic infections, neoplasia of the lower GI tract and inflammatory bowel disease. IgA may be used as an aid in the diagnosis of ataxia telangiectasia, in the differentiation of M-components in multiple myeloma, and in the evaluation of progression of IgA myeloma. Decreased levels of IgA may be found in isolated genetic deficiency, combined immunodeficiency disorders, non-IgA multiple myeloma or macroglobulinemia.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.