A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Human Papillomavirus-High Risk

Message

This test determines the presence of E6/E7 mRNA from 14 high-risk HPV genotypes (16, 18, 31, 33, 35, 39,45, 51, 52, 56, 58, 59, 66, and 68).



Test Code
HPVH


CPT Codes
87621

Preferred Specimen

PreservCyt Thin Prep PAP



Instructions

PRESERVCYT THIN PREP PAP- COLLECT ACCORDING TO PACKAGE INSERT.



Transport Container

PRESERVCYT THIN PREP PAP



Transport Temperature
ROOM TEMP.


Specimen Stability
30 DAYS


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
SPECIMEN NOT COLLECTED FOR CORRECT SOURCE OR TEST REQUESTED BEYOND STABILITY OF PATIENT SAMPLE.


Methodology
TRANSCRIPTION-MEDIATED AMPLIFICATION (TMA)

Setup Schedule

MONDAY-FRIDAY EVENING.



Report Available
2 DAY


Reference Range

NEGATIVE



Clinical Significance

HPV E6/E7 oncoproteins mediate the development of cervical cancer.  Their overexpression, which can be measured as E6/E7 messenger RNA (mRNA) transcripts, is associated with a significant increase risk of cervical intraepithelial neoplasia (CIN) and cervical carcinoma.





The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.