Hepatitis B Surface Antibody

Test Code

HBSAB

Alias/See Also

aHBs, Anti-Hepatitis B surface ab

CPT Codes
86706

Preferred Specimen

Serum (gold or red top tube)

Minimum Volume

1mL

Transport Container

Serum (gold or red top) Tube

Transport Temperature

Room Temperature or Refrigeration

Specimen Stability

Room Temperature - 8 hours; Refrigeration - 48 hours

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Turbidity, Equivocal readings, Quantity Not Sufficient, EDTA (purple top tube) Contamination, IV Contamination

Methodology
Chemiluminescence

Setup Schedule

Daily upon receipt

Report Available

Upon completion of analysis

Reference Range

Interpretation:

Negative: The sample is negative for anti-HBs and the patient is not immune to Hepatitis B

Positive: anti-HBs has been detected at levels consistent with protective immunity against HBV
|infection

Any test result that falls above the maximum threshold for a "Negative" result but below the minimum threshold for a "Positive" result will be cancelled and specimen should be recollected at a later time.

Clinical Significance

Individuals who have had HBV infection in the past and have now resolved their HBV infection usually demonstrate both anti-HBs and antibody to hepatitis B core antigen (anti-HBc) in their serum. The absence of both anti-HBs and anti-HBc is indicative of susceptibility to HBV infection, and can identify individuals who may benefit from vaccination. Both plasma derived and recombinant protein based vaccines have been developed and shown to be effective in inducing immunity to HBV through production of antibodies to HBsAg. Anti-HBs testing is useful for identifying HBV susceptible individuals in pre- and post-vaccination screening programs.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.