| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Alkaline Phosphatase
Test CodeCPT Codes
84075
Preferred Specimen
Serum (gold top) tube
Minimum Volume
Other Acceptable Specimens
Transport Container
Serum (gold top) tube or Lithium Heparin Plasma (green top) tube
Transport Temperature
Specimen Stability
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Methodology
Colorimetric
Setup Schedule
Daily upon receipt
Report Available
Reference Range
| Birth - 4 Years: | 145 - 320 U/L |
| 4 - 7 Years: | 150 - 380 U/L |
| 7 - 10 Years: | 175 - 420 U/L |
| 10 - 16 Years (Female): | 130 - 560 U/L |
| 10 - 16 Years (Male): | 135 - 530 U/L |
| 16 - 19 Years (Female): | 50 - 130 U/L |
| 16 - 19 Years (Male): | 65 - 260 U/L |
| 19 Years and Older: | 36 - 126 U/L |
Clinical Significance
Alkaline phosphatase is present mainly in bone, liver, kidney, intestine, placenta, and lung. Serum alkaline phosphatase may be elevated in increased bone metabolism, for example, in adolescents and during the healing of a fracture; primary and secondary hyperparathyroidism; Paget’s disease of bone; carcinoma metastatic to bone; osteogenic sarcoma; and Hodgkin’s disease if bones are invaded. Hepatobiliary diseases involving cholestasis, inflammation, or cirrhosis increase alkaline phosphatase activity; alkaline phosphatase activity may be increased in renal infarction and failure and in the complications of pregnancy. Low alkaline phosphatase activity may occasionally be seen in hypothyroidism.