Anti Neut Cytoplasmic Ab Panel

Test Code

ANCAP

Alias/See Also

Vasculitis Panel; pANCA; cANCA

CPT Codes
83516; 83876

Includes

PR3 antibody(proteinase 3); MPO antibody(myeloperoxidase) and GBM antibody(glomerular base membrane)

Preferred Specimen

serum

Minimum Volume

1.0 mL

Other Acceptable Specimens

none

Instructions

No anticoagulants or preservatives added to sample.

Transport Container

RED/1

Transport Temperature

stored at 2-8C for no longer than 48 hours; store at -20C or below after 48 hours.

Specimen Stability

48 hours at 2-8C; indefinitely at -20C or below.

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolyzed, icteric, lipemic or bacterially contaminated sera

Methodology
MBA

Setup Schedule

Wednesday and Sunday

Report Available

3 days

Reference Range

Negative - <100 AU/mL
Positive - >120 AU/mL
Equivocal - 100 to 120 AU/mL

Clinical Significance

The Vasulitis panel is intended for the qualitative and semi-quantitative detection of IgG class antibody to 2 separate ANCA Antigens (Myeloperoxidase and Proteinase 3) in human serum. The test is intended to be used as an aid in the diagnosis of various autoimmune vasculitic disorders characterized by elevated levels of anti-neutrophil cytoplasmic antibodies (ANCA). MPO and/or PR3 may be associated with autoimmune disorders such as Wegener’s Granulomatosis, ICGN, MPA and PRS.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.