BK Virus DNA, Quantitative Real-Time PCR, Urine [16581X]

Test Code

CPT Codes

Preferred Specimen
0.7 mL random urine, unpreserved, submitted in a sterile plastic leak-proof container

Minimum Volume
0.3 mL

Collect urine without preservative.

Transport Temperature

Specimen Stability
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days

Real-Time Polymerase Chain Reaction (RT-PCR)

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Daily a.m.; Report available: 1 day

Reference Range
<500 copies/mL

Clinical Significance
This test is used to determine the presence of BK virus DNA in patients' specimens. Detection of the virus in these specimens may be indicative of an active infection, as PCR detects the presence of the virus, and not the hosts reaction to the virus. Polyomavirus BK DNA detection in urine or plasma is associated with an increased risk of graft rejection in renal recipients. Quantitative testing may indicate change in risk over time. This is a quantitative molecular test, with a linear range of 500-500,000,000 copies/mL.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.