hs-CRP

Test Code
10124

CPT Codes
86141

Preferred Specimen
1 mL serum

Minimum Volume
0.5 mL

Other Acceptable Specimens
Plasma collected in a: sodium heparin or lithium (green-top), or EDTA (lavender-top), or EDTA (royal blue-top) tube

Transport Container
Plastic screw-cap vial

Transport Temperature
Room temperature

Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 90 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic

Methodology
Nephelometry

Setup Schedule
Set up: Mon-Sat p.m.; Report available: Next day

Limitations
Oral contraceptives, IUDs, pregnancy, and menstruation may raise hs-CRP levels.  Levels are lowest during ovulation.

Reference Range
For ages >17 years:
hs-CRP
 (mg/L)
Risk According to AHA/CDC Guidelines
<1.0
Lower relative cardiovascular risk.
1.0-3.0
Average relative cardiovascular risk.
3.1-10.0


Higher relative cardiovascular risk.
Consider retesting in 1 to 2 weeks to exclude a benign transient elevation in the baseline CRP value secondary to infection or inflammation.
>10.0
Persistent elevation, upon retesting, may be associated with infection and inflammation.


Clinical Significance

Useful in predicting risk for cardiovascular disease.





The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.