Tissue Transglutaminase Antibody Panel

Test Code
11073

CPT Codes
83516 (x2)

Includes
tTG IgA and IgG Antibodies

Preferred Specimen
1 mL serum

Minimum Volume
0.5 mL

Transport Container
Plastic screw-cap vial

Transport Temperature
Room temperature

Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic

Methodology
Immunoassay (IA)

Setup Schedule
Set up: Tues-Sat a.m.; Report available: Next day

Reference Range
Tissue Transglutaminase Antibody, IgG
<6 U/mL No antibody detected
≥6 U/mL Antibody detected
Tissue Transglutaminase Antibody, IgA
<4 U/mL No antibody detected
≥4 U/mL Antibody detected


Clinical Significance
Tissue Transglutaminase Antibody, IgA, is useful in diagnosing gluten-sensitive enteropathies, such as Celiac Sprue Disease, and an associated skin condition, dermatitis herpetiformis. The IgG test is useful in patients who are IgA-deficient. The IgG test also provides support for gluten-sensitive enteropathies beyond the IgA test.



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.