Tacrolimus, Highly Sensitive, LC/MS/MS

Test Code

70007

CPT Codes
80197

Preferred Specimen

2 mL whole blood collected in an EDTA (lavender-top) tube

Patient Preparation
Collect specimen 1 hour prior to next dose (12 hour trough)

Minimum Volume

1 mL

Transport Container

EDTA (lavender-top) tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 7 days
Frozen: 60 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Clotted specimen

Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Mon-Sat; Report available: Next day

Reference Range

No definitive therapeutic or toxic ranges have been established. Optimal blood drug levels are influenced by type of transplant, patient response, time post-transplant, co-administration of other drugs, and drug formulation.
The following trough range is a suggested guideline: 5.0-20.0 mcg/L

Clinical Significance

Tacrolimus is an immunosuppressant drug which has been shown to be effective for the treatment of rejection following transplantation.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.