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FISH, Follicular Lymphoma, IGH/BCL2, t(14,18), TC
Test Code12616
CPT Codes
88271 x 2, 88275<br>Restricted Client Code - Tech Only
Preferred Specimen
5 mL whole blood or 3 mL bone marrow collected in a sodium heparin (green-top) tube, sodium heparin (royal blue-top) tube, or lead-free, sodium heparin (tan-top) tube, or
5 X 5 mm fresh tissue collected in culture transport media or sterile container with Hanks' or Ringers solution, or
Formalin-fixed paraffin-embedded tissue
5 X 5 mm fresh tissue collected in culture transport media or sterile container with Hanks' or Ringers solution, or
Formalin-fixed paraffin-embedded tissue
Minimum Volume
1 mL
Instructions
3-5 mL whole blood or 1-3 mL bone marrow collected in sodium heparin tube, 5 X 5 mm Fresh tissue in sterile container, Formalin Fixed Paraffin Embedded Tissue.
Specimen viability decreases during transit. Send specimen to testing laboratory for viability determination. Do not freeze. Do not reject.
Transport Temperature
Room temperature
Specimen Stability
See Instructions
Methodology
Fluorescence In Situ Hybridization (FISH)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Daily; Report available: 5 days
Reference Range
See Laboratory Report
Clinical Significance
Translocation t(14;18)(q32;q21.3) is assayed by FISH with probes from the regions IGH (14q32) and BCL2 (18q21.3) this assay is useful to diagnose follicular lymphoma (>75%) and diffuse large cell lymphomas (25%).