Chromosome Analysis, Tissue with Reflex to Microarray, ClariSure® Oligo-SNP

Test Code
91126


CPT Codes
88233, 88262

Includes
If Chromosome Analysis result is "Tissue has no growth", then Chromosomal Microarray, POC, ClariSure® Oligo-SNP will be performed at an additional charge (CPT code(s): 81229).


Preferred Specimen
5x5 mm tissue collected in a sterile container in Hanks', Ringer's solution or culture medium with antibiotics


Minimum Volume
2x3 mm


Instructions
Clinical history/reason for referral is required with test order.

Ship at room temperature. Specimen viability decreases during transit. Do not freeze. Do not reject.


Transport Temperature
Room temperature


Specimen Stability
Room temperature: Preferred
Refrigerated: Acceptable
Frozen: Unacceptable


Methodology
Culture • Karyotype • Microscopy

Setup Schedule
Set up: Daily; Report available: Chromosomes report in 15 days (If needed, array reports 10 days later)


Reference Range
See Laboratory Report


Clinical Significance
Chromosome analysis of products of conception (POC) can detect fetal chromosome abnormalities that are associated with approximately one-half of all first trimester spontaneous abortions. Since chromosome analysis on products of conception has an increased failure rate, this test will reflex to chromosomal microarray if chromosome analysis fails. Chromosomal microarray (CMA) detects aneuploidies, deletions and duplications below the resolution of chromosome analysis (karyotyping), and long continuous regions of homozygosity.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.