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ZAP70, IHC with Interpretation

Test Code
90192


CPT Codes
88342

Preferred Specimen
Formalin-fixed, paraffin-embedded tissue block


Other Acceptable Specimens
Minimum: 3 unstained, positively charged slides


Instructions
Please include surgical pathology report.


Transport Container
IHC Specimen Transport Kit


Transport Temperature
Room temperature


Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable


Methodology
Immunohistochemistry

Setup Schedule
Set up: Mon-Fri a.m.; Report available: 3 days


Reference Range
Interpretive report


Clinical Significance
The T-cell kinase ZAP70 is anomalously expressed in the more aggressive, pre-germinal center subset of B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma. Expression of ZAP70 by immunohistochemistry is well-correlated with overexpression of ZAP70 by transcript analysis or immunohistochemistry.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.