Uroplakin, IHC with Interpretation

Test Code
90188


CPT Codes
88342

Preferred Specimen

1 formalin-fixed, paraffin-embedded tissue block



Other Acceptable Specimens
3 unstained slides, positively charged, submitted in an IHC Specimen Transport Kit


Instructions
Please include surgical pathology report.


Transport Container
IHC Specimen Transport Kit


Transport Temperature
Room temperature


Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable


Methodology
Immunohistochemistry

Setup Schedule
Set up: Mon-Fri a.m.; Report available: 3 days


Reference Range
Interpretive report


Clinical Significance
Uroplakin III is a suface marker of urothelium, that is
commonly used to identify urothelial carcinoma in
metastatic lesions (approx 60% sensitive). However, it is
important to recognize that high-grade urothelial
carcinomas may lose expression of this marker.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.