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TRAcP, IHC with Interpretation [40020X]
Test Code40020
CPT Codes
88342
Preferred Specimen
1 formalin fixed paraffin block
Minimum Volume
1 block
Other Acceptable Specimens
3 Slides Unstained, positively charged slides IHC Specimen Transport Kit
Instructions
Please include surgical pathology report.
Transport Container
IHC Specimen Transport Kit
Transport Temperature
Room temperature
Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: DO NOT FREEZE
Refrigerated: Indefinitely
Frozen: DO NOT FREEZE
Methodology
Immunohistochemistry
Setup Schedule
Set up: Mon-Fri Morning; Report available: 3 days
Reference Range
Interpretive report
Clinical Significance
The histochemical identification of hairy cell leukemia via tartrate-resistant acid phosphatase assay has been a standard for over two decades. Anti-TRAcP antibody labels the cells of hairy cell leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osterclasts, which also express abundant TRAcP activity.