Serotonin Release Assay (SRA), Unfractionated Heparin

Test Code

14627

CPT Codes
86022

Preferred Specimen

1 mL frozen serum

Minimum Volume

0.4 mL

Transport Container

Transport tube

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 6 months

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Received room temperature • Received refrigerated

Methodology
Radiobinding Assay (RBA)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Sun-Fri; Report available: 1-2 days

Reference Range

See Laboratory Report

Clinical Significance

Any patient with an unexplained fall in the platelet count of >40% during or after cessation of heparin therapy should be suspected of hit-heparin induced thrombocytopenia. This test is a functional assay of the PFU-antibody complex with heparin.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.