Rickettsia conorii Antibody Panel, IFA

Test Code

15332

CPT Codes
86757 (x2)

Preferred Specimen

1 mL serum

Minimum Volume

0.2 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Methodology
Indirect Immunofluorescence Assay (IFA)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Tues, Sat; Report available: 2-5 days

Reference Range

Rickettsia conorii Ab (IgG)	<1:64 titer
Rickettsia conorii Ab (IgM)	<1:64 titer

Clinical Significance

Rickettsia conorii infection, also known as Boutonneuse fever or Mediterranean spotted fever, is found in India, Africa, and the Mediterranean area. Due to the high degree of DNA homology (90%) between R. conorii and R. rickettsii, antibodies from most patients with R. conorii infection are also detected in assays for R. rickettsii antibodies. IgM reactivity in the absence of IgG reactivity may represent a false positive reaction. Recent infection should be confirmed by demonstrating either IgG seroconversion or a fourfold or greater increase in IgG titer when acute and convalescent sera are tested in parallel.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.