Protoporphyrins, Fractionation, Whole Blood

Test Code
17802


CPT Codes
84202<br>Limited Access Code

Preferred Specimen
4 mL whole blood collected in sodium heparin (green-top) tube


Patient Preparation
Patient should abstain from alcohol for 24 hours prior to specimen collection.
Include a list of medications the patient is currently taking.

Minimum Volume
3 mL


Other Acceptable Specimens
Whole blood collected in a metal-free heparin (dark blue-top) tube, or EDTA (lavender-top) tube


Instructions
Immediately place specimen on wet ice


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: Unacceptable


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis


Methodology
High-Perform Liqd Chromatography-Fluorescence Detection

FDA Status
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

Setup Schedule
Set up: Mon, Wed, Fri; Report available: 2-5 days


Reference Range
Free Protoporphyrin: <20 mcg/dL
Zinc-Complexed Protoporphyrin: <60 mcg/dL


Clinical Significance

Evaluating patients with possible diagnoses of erythropoietic protoporphyria or X-linked dominant protoporphyria

Establishing a biochemical diagnosis of erythropoietic protoporphyria and X-linked dominant protoporphyria





The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.