Progesterone, LC/MS

Test Code

17183

CPT Codes
84144

Preferred Specimen

1 mL serum collected in a red-top tube (no gel)

Minimum Volume

0.25 mL

Other Acceptable Specimens

Plasma collected in: EDTA (royal blue-top) tube, sodium heparin (green-top) tube, lithium heparin (green-top) tube, or EDTA (lavender-top) tube

Instructions

Collect blood in a Vacutainer® with no additives. Allow blood to clot (10-15 minutes) at room temperature. Centrifuge and separate the serum from the cells.

Transport Container

Plastic screw-cap vial

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 72 hours
Refrigerated: 14 days
Frozen: 2 years

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Serum separator tubes (SST) • Gross hemolysis

Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Sun-Fri; Report available: 3-6 days

Reference Range

Pediatric Males

<30 days	Not established
1 month-17 years	≤0.5 ng/mL

Pediatric Females

<30 days	Not established
1 month-11 years	≤0.5 ng/mL
12 years	≤7.8 ng/mL
13 years	≤10.7 ng/mL
14 years	≤12.5 ng/mL
15 years	≤12.1 ng/mL
16-17 years	≤11.7 ng/mL

Adult Males

18-29 years	≤0.3 ng/mL
30-39 years	≤0.2 ng/mL
40-49 years	≤0.2 ng/mL
50-59 years	≤0.2 ng/mL

Adult Females

Pre-Menopausal Mid Follicular	≤0.3 ng/mL
Pre-Menopausal Surge	0.1-1.5 ng/mL
Pre-Menopausal Mid Luteal	6.7-22.2 ng/mL
Postmenopausal Phase	≤0.2 ng/mL

Clinical Significance

This test (1) establishes the presence of a functioning corpus lutem or luteal cell function, (2) confirms basal body temperature measurements of the occurrence of ovulation (3) affords an indication of the day of ovulation, (4) assesses placental function during pregnancy.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.