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PMS2, IHC with Interpretation
Test Code16997
CPT Codes
88342
Preferred Specimen
Formalin-fixed, paraffin-embedded tissue block
Other Acceptable Specimens
Minimum: 3 unstained, positively charged tissue slides
Instructions
Please include surgical pathology report.
Transport Container
IHC Specimen Transport Kit
Transport Temperature
Room temperature
Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable
Refrigerated: Indefinitely
Frozen: Unacceptable
Methodology
Immunohistochemistry (IHC)
Setup Schedule
Set up: Mon-Fri; Report available: 2 days
Reference Range
See Laboratory Report
Clinical Significance
Defects in mismatch repair systems cause elevated spontaneous mutation rates and increased instability of DNA microsatellite repetitive sequences expressed.