PAX8, IHC without Interpretation

Test Code
90224


CPT Codes
88342

Preferred Specimen
1 formalin fixed paraffin block submitted in IHC Specimen Transport Kit


Minimum Volume
1 block • 3 slides


Other Acceptable Specimens
3 Slides Unstained, positively charged slides IHC Specimen Transport Kit


Instructions
Please include surgical pathology report


Transport Temperature
Room temperature


Specimen Stability
Room Temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Do Not Freeze


Methodology
Immunohistochemistry (IHC)

Setup Schedule
Set up: Mon-Fri; Report available: Next day


Reference Range
See Laboratory Report


Clinical Significance
PAX8, a nuclear transcription factor, is expressed, along with PAX2, in renal cell carcinoma, but not in urothelial carcinoma (which is positive for uroplakin III and P63). Other uses include detection of metastatic ovarian serous tumors (as opposed to mesothelioma).




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.