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PAX8, IHC with Interpretation

Test Code
90174


CPT Codes
88342

Preferred Specimen
Formalin-fixed, paraffin-embedded tissue block


Other Acceptable Specimens
Minimum: 3 unstained slides, positively charged


Instructions
Please include surgical pathology report.


Transport Container
IHC Specimen Transport Kit


Transport Temperature
Room temperature


Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable


Methodology
Immunohistochemistry

Setup Schedule
Set up: Mon-Fri a.m.; Report available: 3 days


Reference Range
Interpretive report


Clinical Significance
PAX8, a nuclear transcription factor, is expressed, along with PAX2, in renal cell carcinoma but not in urothelial carcinoma (which is positive for uroplakin III and P63). Other uses include detection of metastatic ovarian serous tumors (as opposed to mesothelioma).




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.