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PAX-5, IHC with Interpretation [40039X]
Test Code40039
CPT Codes
88342
Preferred Specimen
Minimum: 1 formalin-fixed, paraffin-embedded block, submitted in IHC Specimen Transport Kit, room temperature
Other Acceptable Specimens
Minimum: 3 unstained, positively charged slides, submitted in IHC Specimen Transport Kit, room temperature
Instructions
Please include surgical pathology report.
Transport Container
IHC Specimen Transport Kit
Transport Temperature
Room temperature
Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable
Refrigerated: Indefinitely
Frozen: Unacceptable
Methodology
Immunohistochemical Stain
Setup Schedule
Mon-Fri a.m.; Report available: 2 days
Reference Range
Interpretive report
Clinical Significance
Pax genes are a family of developmental control genes that encode nuclear transcription factors and have been implicated in the control of mammalian development. PAX-5 is a B cell specific transcription factor that is expressed in pro B-cells, pre-B and mature B cells, and subsequently in all stages of B cell development until that plasma cell stage in which it is down regulated.
