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Lactoferrin, Qualitative, Stool
Test Code10156
CPT Codes
83630
Preferred Specimen
1 gram undiluted stool collected in a sterile, dry leak-proof container
Minimum Volume
0.3 grams
Instructions
Collect undiluted feces in clean, dry, sterile, leak-proof container. Do not add fixative or preservative. Patients may collect stool and hold at room temperature until it can be properly frozen. The time held at room temperature must not exceed 48 hours from time of collection.
Specimens can be delivered to Patient Service Center (PSC) or Physician's office for freezing and delivery to the laboratory. Once specimen has been frozen, do not thaw.
Specimens can be delivered to Patient Service Center (PSC) or Physician's office for freezing and delivery to the laboratory. Once specimen has been frozen, do not thaw.
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 14 days
Frozen: 21 days
Refrigerated: 14 days
Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Specimen received in transport media
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Tues, Thurs, Sat; Report available: Next day
Limitations
False-positive results are observed in breast-fed infants.
Reference Range
Negative
Clinical Significance
Lactoferrin is a marker for fecal leukocytes and a positive result is an indicator of intestinal inflammation. This elevation may be caused by acute infectious colitis or active inflammatory bowel disease (IBD). The test may not be appropriate in immunocompromised persons. In addition, this test is not FDA cleared for patients with a history of HIV and/or hepatitis B and C, patients with a history of infectious diarrhea (within 6 months), and patients having had a colostomy and/or ileostomy within 1 month.
