Lactate Dehydrogenase (LD)

Test Code
593


CPT Codes
83615

Preferred Specimen
1 mL serum collected in a serum separator tube (SST)


Minimum Volume
0.5 mL


Other Acceptable Specimens
Plasma collected in a sodium or lithium heparin (green-top) tube


Instructions
Do not refrigerate or freeze.

For fluids, please use test codes:
17589X, LD, Pleural Fluid
17588X, LD, Peritoneal Fluid
17658X, LD, Synovial Fluid
17647X, LD, Pericardial Fluid
1687X LD, CSF
*Fluids other than those listed are not acceptable.


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 14 days
Refrigerated: 48 hours
Frozen: Unacceptable


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis


Methodology
Spectrophotometry (SP)

Setup Schedule
Set up: Sun-Fri a.m. and nights, Sat a.m.; Report available: Next day


Reference Range
  Male (U/L) Female (U/L)
<1 Month 125-735 145-765
1-11 Months 170-450 190-420
1-3 Years 155-345 165-395
4-6 Years 155-345 135-345
7-10 Years 140-270 140-270
11-13 Years

110-250

110-250
14-17 Years 110-230 110-230
18-49 Years 100-220 100-200
>49 Years 120-250 120-250


Clinical Significance
Elevations in serum lactate dehydrogenase occur from myocardial infarction, liver disease, pernicious and megaloblastic anemia, pulmonary emboli, malignancies, and muscular dystrophy. Since lactic dehydrogenase is present in many body tissues, it's diagnosis usefulness is limited. Tissue specificity may be enhanced by isoenzyme analysis.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.