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Interleukin-1 Beta
Test Code1757
CPT Codes
83520
Preferred Specimen
1 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.5 mL
Other Acceptable Specimens
3.2% sodium citrate (light blue-top) tube
Instructions
Cytokine levels may demonstrate diurnal variation. Recommend cytokine levels be determined at the same time of day for improved longitudinal comparison.
Transport Container
Plastic screw-cap vial
Transport Temperature
Frozen
Specimen Stability
Room temperature: 24 hours
Refrigerated: 48 hours
Frozen: 21 days
Refrigerated: 48 hours
Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Gross lipemia • Specimen containing visible particulate matter • SST® • Received room temperature • Received refrigerated
Methodology
Enzyme Linked Immunosorbent Immunoassay (ELISA)
FDA Status
This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.
Setup Schedule
Set up: Wed night; Report available: 7 days
Reference Range
<3.9 pg/mL
Clinical Significance
IL-1 is a pro-inflammatory cytokine, and has also been associated with bone formation, insulin secretion, appetite regulation, fever reduction, neuronal development, and other conditions.
