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Hemoglobin S Post Transfusion Assessment [17469X]
Test Code135251
CPT Codes
83020
Includes
Hemoglobinopathy Screen, and confirmation by HPLC
Preferred Specimen
5 mL whole blood collected in an EDTA (lavender-top) tube
Minimum Volume
1 mL
Instructions
Please provide the patient's phenotype when requesting this test code.
Note: Testing will include Hemoglobinopathy Screen and confirmation by HPLC. No pathologist or technical interpretation will accompany the report. The report will include the percentage of Hemoglobin S (HbS), and Hemoglobin C (HbC), if the patient is SC.
Note: Testing will include Hemoglobinopathy Screen and confirmation by HPLC. No pathologist or technical interpretation will accompany the report. The report will include the percentage of Hemoglobin S (HbS), and Hemoglobin C (HbC), if the patient is SC.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 72 hours
Refrigerated: 7 days
Frozen: Unacceptable
Refrigerated: 7 days
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Clotted
Methodology
Electronic Sizing and Counting/Cytometry • Capillary Electrophoresis followed by, if necessary, High Performance Liquid Chromatography, Solubility
Setup Schedule
Set up: Mon-Sat; Report available: 1-3 days
Reference Range
See Laboratory Report
Clinical Significance
This profile is to be used for monitoring the effects of transfusion/exchange transfusion and hemoglobin F levels post hydroxyurea treatment in patients with known sickle cell anemia or sickle cell disease.
