HBME-1, IHC without Interpretation

Test Code
90214


CPT Codes
88342

Preferred Specimen
Formalin-fixed paraffin embedded tissue


Other Acceptable Specimens
3 slides unstained, positively charged slides


Transport Container
IHC specimen transport kit


Transport Temperature
Room temperature


Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received frozen


Methodology
Immunohistochemistry

Setup Schedule
Monday-Friday Morning
Report available: Next Day


Clinical Significance
HBME-1, first identified on the membrane/microvilli of mesothelial cells, stains mesothelioma. However, it can also be seen in up to 20-30% of carcinomas, but usually showing a cytoplasmic expression pattern in those cases.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.